2182-5173 2182-5173 S2182-51732023000500458 10.32385/rpmgf.v39i5.13416 Portugal Portugal Portugal Portugal 31 10 2023 31 10 2023 39 5 458 470

1 2018 44 6 6 1195-203 2 2018 3 2012 4 1997 47 421 421 515-20 5 2015 17 10 10 84 6 2019 17 1 1 227 7 2016 173 4 4 362-72 8 1998 2 9 2019 32 1 1 70-7 10 2015 72 12 12 1172-81 11 2013 3 4 4 12 National Institute for Health and Care Excellence 2014 13 National Institute for Health and Clinical Excellence 2014 14 2003 178 S9 S9 S71-5 15 2016 94 8 8 635-41 16 2018 212 1 1 1-3 17 World Health Organization 2017 18 2017 19 2010 22 2 2 198-202 20 1993 21 2017 15 1 1 63 22 2002 20 2 2 5-17 23 Diário da República 2019 169 169 24 Direção-Geral da Saúde 2011 25 2010 81 5 5 617-22 26 2012 27 2006 19 1 1 1-8