SciELO - Scientific Electronic Library Online

 
vol.17 issue2Bilateral iliac aneurysms and concomitant severe multilevel occlusive arterial disease: staged hybrid procedure as solution to a nightmarePost-transplant renal artery kinking associated with the patient's position: case-report author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • Have no similar articlesSimilars in SciELO

Share


Angiologia e Cirurgia Vascular

Print version ISSN 1646-706X

Angiol Cir Vasc vol.17 no.2 Lisboa June 2021  Epub June 30, 2021

 

Clinical Case

Superior mesenteric artery pseudoaneurysm rupture: a rare complication of pancreatic surgery

Rotura de falso aneurisma da artéria mesentérica superior: uma rara complicação da cirurgia pancreática

Carolina Semião1 

Daniel Brandão1 

Clara Nogueira1 

Ricardo Gouveia1 

Rita Augusto1 

Nuno Coelho1 

Evelise Pinto1 

João Ribeiro1 

João Peixoto1 

Luís Fernandes1 

Alexandra Canedo1 

1 Serviço de Angiologia e Cirurgia Vascular, Centro Hospitalar Universitário Vila Nova de Gaia / Espinho, Vila Nova de Gaia, Portugal


Abstract

Pseudoaneurysms after gastro-intestinal tract surgery are rare. Most of them occur after biliary tract and pancreatic surgery. They can lead to potentially serious consequences, such as rupture, hemorrhage and death. For these reasons, pseudoaneurysms should be diagnosed and treated as soon as possible.

Keywords: Superior mesenteric artery pseudoaneurysm; Pseudoaneurysm rupture; Endovascular treatment

Resumo

A formação de pseudoaneurismas após cirurgia gastrointestinal é rara. A maioria ocorre após cirugia do tracto biliar e cirurgia pancreática. Os pseudoaneurismas podem ter consequências potencialmente fatais, tais como rotura e hemorragia. Por esse motivo, esta entidade deve ser diagnosticada e tratada rapidamente.

Palavras-chave: Pseudoaneurisma da artéria mesentérica superior; Rotura pseudoaneurisma; Tratamento endovascular

Case Report

A 61-year-old man diagnosed with a pancreatic tumor, was submitted to a Whipple procedure and hemicolectomy. In the post-operative period, he developed a pancreatic fistula treated with octreotide. Patient was admitted in the emergency room, 9 days after discharge, with hemodynamic instability, fever and a spontaneous hematic drainage through previous drain incision.

A surgical revision was performed, leaving an abdominal drainage, and meropenem was prescribed empirically. Four days after, he presented a spontaneous hematic drainage of 800 ml and persistent fever. Angio-CT scan revealed the rupture of a large pseudoaneurysm arising from the proximal portion of the superior mesenteric artery (SMA) (figure 1). The patient was immediately transferred to our center and forwarded to the angio suite. A selective SMA angiography confirmed the diagnosis. A 7×59mm stent graft (Advanta V12) was successfully deployed across the pseudoaneurysm, with immediate clinical and imagiological resolution (figure 2). On follow-up, patient maintained complete pseudoaneurysm exclusion and patency of the stent graft.

Discussion

Postoperative SMA pseudoaneurysm in the face of pancreatic surgery is a rare yet dangerous complication(1).

Figure 1 Angiography showing rupture of the superior mesenteric artery aneurysm. 

Figure 2 Superior mesenteric artery stent-graft deployment excluding the tear.. 

The formation of these pseudoaneurysms is attributed to the release of elastase, which leads to enzymatic autodigestion of adjacent arterial walls(2). Complications of pseudoaneurysms include rupture into the peritoneum, gastrointestinal tract, or rarely, the pancreatic duct. Intermittent gastrointestinal bleeding and crescendo-decrescendo abdominal pain may result. While early post-pancreatectomy hemorrhage occurs by definition within 24h from resection, delayed post-pancreatectomy hemorrhage can occur many days and even weeks later. In the described case, our patient presented with bleeding signs more than a week after surgery(3).

CT scan is currently the gold standard for diagnosis and in this case, the diagnosis was made in the emergency setting with a contrasted CT scan(4).

Delayed post-pancreatectomy hemorrhage represents to date a major cause of postoperative mortality(3); this complication is extremely difficult to manage because of the unstable clinical condition of the patients, wich deteriorates rapidly. In the past, surgical approach was considered the best treatment but it was associated with high rates of morbidity and mortality, besides the challenging postoperative adhesions and inflammation. These issues, have launched the endovascular approach as a less invasive, effective and safe technique with reduced morbi-mortality, when compared with open surgical care.

According to some reports, covered stent-grafts are associated with a diminished risk of recurrent hemorrhage when compared to selective embolization(5).Stent-graft deployment can lead to immediate exclusion of the pseudoaneurysm with a relatively short operative time. Moreover, stent graft implantation has been associated with a lower use of fluoroscopy during the procedure. Although it is a good treatment option, there are some associated complications, such as endoleaks and stent thromboses. Stent migration and consequent bleeding have also been described. Infection of the stent is another serious potential complication, which can happen when contact with gastrointestinal content or infected necrotic tissue occurs(6).

Vascular injuries after pancreatic surgery are associated with a significantly increased morbi-mortality. Early recognition and treatment are essential to optimize damage control and minimize complications. Whenever feasible, endovascular exclusion of a visceral artery pseudoaneurysm is a safe and effective technique with reduced morbi-mortality, when compared with open surgical care.

References

1. Suzuki K, Mori Y, Komada T, Matsushima M, Ota T, Naganawa S. Stent-graft treatment for bleeding superior mesenteric artery pseudo- aneurysm after pancreaticoduodenectomy. Cardiovasc Intervent Radiol 2009;32:762-6. [ Links ]

2. Elton E, Howell D, Amberson S, Dykes T. Combined angiographic and endoscopic management of bleeding pancreatic pseudo- aneurysms. Gastrointest Endosc 1997;46:544-8. [ Links ]

3. Kasumova GG, Eskander MF, Kent TS, et al. Hemorrhage after pancreaticoduodenectomy: does timing matter? HPB (Oxford) 2016;18:861-9. [ Links ]

4. Scott Cowan, MD et al. Superior mesenteric artery pseudoaneurysm successfully treated with polytetrafluoroethylene covered stent J Vasc Surg 2002;35:805-7 [ Links ]

5. Nakai M, Sato H, Sato M, Ikoma A, Sanda H, Nakata K, Minamiguchi H, Kawai N, Sonomura T, Nishimura Y and Okamura Y. Endovascular stenting and stent-graft repair of a hemorrhag- ic superior mesenteric artery pseudoaneurysm and dissection associated with pancreatico- duodenectomy. J Vasc Interv Radiol 2012; 23: 1381-1384. [ Links ]

6. Offroy R, Guiu B, D’Athis P, Mezzetta L, Gagnaire A, Jouve JL, Ortega-Deballon P, Cheynel N, Cercueil JP, Krausé D. Arterial embolotherapy for endoscopically unmanage- able acute gastroduodenal hemorrhage: pre- dictors of early rebleeding. Clin Gastroenterol Hepatol 2009; 7: 515-523. [ Links ]

7. Beyer L, Bonmardion R, Marciano S, Hartung O, Ramis O, Chabert L, Leone M, Emungania O, Orsoni P, Barthet M, Berdah SV, Brunet C and Moutardier V. Results of non-operative therapy for delayed hemorrhage after pancreaticoduo- denectomy. J Gastrointest Surg 2009; 13: 922-928. [ Links ]

Received: August 05, 2020; Accepted: March 27, 2021

Autor para correspondência Correio eletrónico: anasemiao1@gmail.com (C. Semião)

Creative Commons License This is an open-access article distributed under the terms of the Creative Commons Attribution License