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Millenium - Journal of Education, Technologies, and Health

Print version ISSN 0873-3015On-line version ISSN 1647-662X

Mill  no.19 Viseu Oct. 2022  Epub Oct 31, 2022

https://doi.org/10.29352/mill0219.28017 

Life and health sciences

Non-invasive mechanical ventilation in severe acute respiratory syndrome in patients hospitalized for COVID-19: systematic review protocol

Ventilação mecânica não invasiva na síndrome respiratória aguda grave em pacientes internados por COVID-19: protocolo de revisão sistemática

Ventilación mecánica no invasiva en síndrome respiratorio agudo serio en pacientes internados por COVID-19: protocolo revisión sistemática

Sara Sabrina Vieira Cirilo1 
http://orcid.org/0000-0002-7347-9927

Raniel da Silva Machado1 
http://orcid.org/0000-0003-0040-2520

Alexandre da Conceição Santos1 
http://orcid.org/0000-0003-4242-9457

Karine Lima Rodrigues1 
http://orcid.org/0000-0001-5631-1615

Baldomero Antonio Kato da Silva1 
http://orcid.org/0000-0001-9337-9563

1 Universidade Federal do Delta do Parnaíba, Parnaíba-PI, Brasil


Abstract

Introduction

Non-Invasive Ventilation is a form of ventilatory support that promotes improvement in several respiratory parameters such as peripheral oxygen saturation, decreased respiratory work, and a significant reduction in the need for intubation and mortality. It is a widely used therapy in the treatment of severe hypoxemia and refractory to oxygen therapy, a clinical condition observed in patients hospitalized for COVID-19.

Objective

Investigate through the scientific literature the interference of Non-Invasive Ventilation in the hospital outcome of patients with severe acute respiratory syndrome triggered by COVID-19.

Methods

The review will follow the guidelines established by the Joanna Briggs Institute methodology and Preferred Report Items for Systematic Reviews and Meta-Analyses. Two independent reviewers will perform the search, quality assessment, data extraction, and synthesis. The databases used will be PubMed, PEDro, Cochrane Central Register of Controlled Trials, Scielo, and Web of Science. Also, studies published in the grey literature in ProQuest Disserts and Theses Database Science and Google Scholar that meet established criteria will be included.

Results

An initial survey showed that the proper use of Non-Invasive Ventilation administered with a helmet has significant outcomes on the rate of Orotracheal Intubation and Invasive Mechanical Ventilation. There were also studies with outcomes on morbidity and mortality and protocols for use and monitoring.

Conclusion

The results will inform the use of this therapy and its outcomes to promote an effective intervention in hospitalized patients.

Keywords: COVID-19; non-invasive ventilation; hospitalization

Resumo

Introdução

A Ventilação Não Invasiva é uma forma de suporte ventilatório que promove melhoria em diversos parâmetros respiratórios como: saturação periférica de oxigênio, diminuição do trabalho respiratório e redução significativa na necessidade de intubação e mortalidade. É uma terapia amplamente utilizada no tratamento de hipoxemia grave e refratária à oxigenoterapia, uma condição clínica observada nos pacientes hospitalizados por COVID-19.

Objetivo

Investigar através da literatura científica a interferência da Ventilação Não Invasiva no desfecho hospitalar dos pacientes com síndrome respiratória aguda grave desencadeada por COVID-19.

Métodos

A revisão seguirá as normas estabelecidas pela metodologia Joanna Briggs Institute e Preferred Report Items for Systematic Reviews and Meta-Analyses. Dois revisores independentes realizarão as buscas, a avaliação de qualidade, a extração e a síntese dos dados. As bases de dados utilizadas serão a PubMed, PEDro, Cochrane Central Register of Controlled Trials, Scielo, Web of Science, também serão incluídos estudos publicados na literatura cinzenta na ProQuest Disserts and Theses Database Science e no Google Scholar que atendam a critérios estabelecidos.

Resultados

Um levantamento inicial apontou que o uso adequado da Ventilação Não Invasiva administrado com capacete apresenta desfechos significativos sobre a taxa de Intubação Orotraqueal e Ventilação Mecânica Invasiva. Observou-se também estudos com desfechos sobre morbimortalidade e protocolos de utilização e monitoramento.

Conclusão

Os resultados irão informar sobre a utilização dessa terapia e os seus desfechos afim de promover uma intervenção efetiva nos pacientes internados.

Palavras-chave: COVID-19; ventilação não invasiva; hospitalização

Resumen

Introducción

La Ventilación No Invasiva es una forma de soporte ventilatorio que promueve la mejora en varios parámetros respiratorios tales como: saturación periférica de oxígeno, disminución del trabajo respiratorio y una reducción significativa en la necesidad de intubación y mortalidad. Es una terapia ampliamente utilizada en el tratamiento de la hipoxemia severa y refractaria al oxígeno, una condición clínica que se observa en pacientes hospitalizados por COVID-19.

Objetivo

Investigar a través de la literatura científica la interferencia de la Ventilación No Invasiva en la evolución hospitalaria de pacientes con síndrome respiratorio agudo severo desencadenado por COVID-19.

Métodos

La revisión seguirá las pautas establecidas por la metodología del Instituto Joanna Briggs y los elementos de informe preferidos para revisiones sistemáticas y metanálisis. Dos revisores independientes realizarán las búsquedas, la evaluación de la calidad, la extracción y la síntesis de los datos. Las bases de datos utilizadas serán PubMed, PEDro, Cochrane Central Register of Controlled Trials, Scielo, Web of Science, también se incluirán los estudios publicados en la literatura gris en ProQuest Disserts and Theses Database Science y Google Scholar que cumplan con los criterios establecidos.

Resultados

Una encuesta inicial encontró que el uso adecuado de la ventilación no invasiva administrada con un casco tiene resultados significativos en la tasa de intubación orotraqueal y ventilación mecánica invasiva. También se observaron estudios con desenlaces sobre morbimortalidad y protocolos de uso y seguimiento.

Conclusión:

Los resultados informarán el uso de esta terapia y sus resultados para promover una intervención efectiva en pacientes hospitalizados.

Palabras Clave: COVID-19; ventilación no invasiva; hospitalización

Introduction

1. Theoretical framework

Initially detected in December 2019 in Wuhan, China, the new coronavirus (SARS-CoV-2) was pinpointed as the causative agent of the respiratory syndrome that in mid-2020 was named by the World Health Organization (WHO) COVID-19 (Coronavirus disease 2019) and decreed as a global pandemic (Mohamed & Alawna, 2020; Sharma et al., 2021). Currently, the disease has infected over 514 million people worldwide and has been fatal in 6.24 million cases. Studies that have analyzed hospitalization rates in several countries on different continents indicate that approximately 5% to 20.7% of those infected develop the most severe condition, requiring hospitalization for advanced care, emergency medical intervention with intensive care unit (ICU) care, and promotion of respiratory support (Wang et al., 2021; Yilma et al., 2021).

So far four main types of coronaviruses have been identified and are classified according to their propensity to infect certain cells and tissues and by their pathogenic power, they are: α, β, gamma, and delta. Three stages of increasing severity of infection by the new coronavirus are documented, ranging from asymptomatic states to its most severe form as a severe acute respiratory syndrome that may lead to hospitalization with the need for respiratory support or even multiple organ failure and death (Brugge et al., 2021; Polak et al., 2020). Thus, the treatment used for COVID-19 was initially based on the control and/or remission of the manifested symptoms, ranging from drug therapies, and transfusion to non-invasive and invasive ventilatory support therapies (Gavriatopoulou et al., 2021; González-Castro et al., 2021).

The use of non-invasive ventilation (NIV) as a form of ventilatory support when administered appropriately, with continuous monitoring, and with well-defined parameters promotes improvement in various respiratory parameters such as oxygenation and peripheral oxygen saturation, decreased respiratory work, and a significant reduction in the need for intubation and mortality (Navarra et al., 2020; Spadari & Gardenghi, 2020; Wang et al., 2021). The use of this therapy for patients with Covid-19 should always be seen primarily as an additional measure early in the disease process as part of a stepwise approach, at a time when the criteria for intubation have not yet been met or indicate that there is no need (Windisch et al., 2020).

The indication of NIV stems from the fact that it is widely used as a resource with significant results in patients with cardiopulmonary diseases such as Chronic Obstructive Pulmonary Disease (COPD) and Cardiogenic Pulmonary Edema (CPE). In such a way, viral pneumonia caused by the novel coronavirus (SARS-CoV-2), in its severe form (Severe Acute Respiratory Syndrome, SARS), produces severe hypoxemia refractory to oxygen therapy, with pathophysiological changes that have similarities to those found in Acute Respiratory Distress Syndrome (ARDS) and COPD exacerbation pictures. (Osadnik et al., 2017; Weng et al., 2010; Zhan et al., 2012).

Increased mortality as a consequence of delayed intubation and IMV may be linked to inadequate application of NIV and its form of monitoring. However, a clinical update for the treatment of patients with COVID-19 states that in settings with limited access to invasive ventilation or before patients develop severe hypoxemic respiratory failure, NIV may be a useful alternative (Hraiech et al., 2013; Murthy et al., 2020; Nava et al., 2011).

Given the global pandemic scenario caused by COVID-19, a disease that caused the search for hospital beds in many cases, strategies were adopted as the need for installation of NIV and even in more severe situations the IMV for reversal of SARS (Wendel-Garcia et al., 2022). These resources continue to be the subject of much investigation, thus the search for answers regarding the outcomes of NIV in this patient profile is justified as an important object of study. Thus, a systematic review will allow us to identify and analyze through scientific evidence whether NIV interferes in the hospital outcome of patients with the severe acute respiratory syndrome (SARS) triggered by COVID-19.

To this end, the following guiding questions were listed:

  • What are the specificities of the forms of NIV application?

  • Does the form of application influence the patient's prognosis?

  • Are there NIV administration protocols?

2. Methods

This systematic review protocol has already undergone registration submission and validation at PROSPERO under registration number: CRD42022337573.

The proposed systematic review will be conducted according to the JBI methodology for systematic reviews (Peters et al., 2020) and PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) recommendations (Moher et al., 2009).

Inclusion criteria

Participants

This review will include studies that elected hospitalized patients regardless of the ward, aged 18 years or older, who had a laboratory or radiological diagnosis of covid-19 and required noninvasive ventilation respiratory support in different modes and interfaces at some point during their hospitalization.

Intervention

This review will consider studies that evaluated the outcome of using NIV in different settings modes and parameters.

Comparison

The study will include articles that used other respiratory support techniques such as a high-flow nasal cannula, or oxygen therapy by a non-rebreather mask or nasal catheter as a comparator.

Outcome

Did the use of NIV change the length of hospital stay, interfere with the outcome of morbidity and mortality, or the rate of need for invasive mechanical ventilation?

Study type

This systematic review will consider literature published in peer-reviewed journals that cover all types of methodology, randomized clinical trials, experimental and quasi-experimental studies, and systematic reviews with meta-analysis, as well as studies published in the gray literature that meet the inclusion criteria for this study. Case studies, integrative reviews, protocols, guidelines, books, or letters to the reader will not be included.

Search strategy

The search strategies used will delimit the studies that will be included in this review. In order to delineate the study, a first limited search was performed in the PUBMED database to find the scientific literature on the subject and use the Medical Subject Headings (MeSH), subject headings, keywords, and indexing terms of relevant articles on the subject to guide the next searches. In addition, the bibliographic references of articles analyzed during this initial stage of the review will also be used.

The following databases will be used for the study: PubMed, PEDro, Cochrane Central Register of Controlled Trials; Scielo, and grey literature in ProQuest Disserts and Theses Database Science; Web of Science, and Google Scholar as a purpose to obtain a comprehensive overview of the published literature. The proposed search strategy for the PubMed database, applied as an example, can be seen in Table 1.

Table 1 Search strategy for use in PubMed 

Selection of studies and assessment of methodological quality

The selection of studies will occur through a screening procedure carried out by impartial reviewers, who will analyze the titles and abstracts of the scientific articles found in the research, after which a choice will be made of the full texts of the documents eventually selected for final insertion, taking into account the exclusion and inclusion criteria. Any disagreement about the choice or not of any study will be resolved through a third author, who will read the entire article and decide through argumentation and debate with the others.

The PRISMA flow chart will be used to display and specify the final report of all the results of the critical appraisal in narrative and/or tabular formats of each search step, including the reasons taken for the exclusion criteria. For analysis of study methodological quality, the two independent reviewers will use established assessment tools, where eligible studies will be critically assessed and characterized in their quality by the two reviewers. Each study that is included will go through the process of data extraction and summarization (when feasible), regardless of the assessment of the quality of its methodology.

To assess the reliability of the findings, The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) (Schünemann et al., 2013) will be used and a summary of the results will be created using GRADEPro GDT software (McMaster University, ON, Canada). The summary will contain the following information: absolute risks for treatment and control, relative risk estimates, heterogeneity, risk of bias, inconsistency, imprecision, and publication bias.

Data extraction, synthesis, and presentation

The data extraction will be done through an adaptation of the JBI data extraction tool (see table 2). This process will be done individually by each of the two evaluators and, after that, the other evaluators will review the homogeneity and authenticity of the extracted information impartially. The results of the study will be summarized through the use of tables to demonstrate the extracted data using organized and aggregated indicators to verify, present, and synthesize the evidence and findings related to the theme proposed for the research.

Table 2 Data extraction form 

3. Results

The purpose of this systematic review is to include several references that point to the ways of administering NIV in patients with Covid-19-triggered SARS. An initial literature survey points out that the appropriate use of helmet-assisted NIV (HELMET) has significant outcomes on the rate of OTI and MV, but no significant difference in the number of days with support requirement (Grieco et al., 2021). Studies were also observed with outcomes on morbidity and mortality and protocols for use and monitoring (Duan et al., 2017; Guia et al., 2021), and forms of application and interfaces used (Sullivan et al., 2022).

4. Discussion

It becomes necessary to recognize whether the role and effect of the use of Non-Invasive Ventilation in patients with severe acute respiratory syndrome admitted for COVID-19, generated a positive impact or not on morbidity and mortality rates, prevention of orotracheal intubation, and discharges for improvement in the hospitals where these beings were admitted.

As well as to list the protocols used in various services, their forms of application, evaluation, and predictive indices of NIV failure, such as the HACOR scale and PaO2/FiO2 ratio (Duan et al., 2017; Guia et al., 2021). It is also necessary to recognize its indications and contraindications in this profile of patients, the safety practices related to the dissemination of contamination by COVID-19, and also the comparison with other techniques of ventilatory support/oxygen therapy (Grieco et al., 2021; Sullivan et al., 2022).

Since it is a disease with a worldwide impact and very high rates of hospitalization since the beginning of the pandemic, leading to reflection on the current reality of intensive care units in Brazil and worldwide. Thus, this study brings the need to identify what is being done in the current practice, what are the nuances and outcomes and use them as a basis for further inquiries.

Conclusion

The systematic review developed from the definitions and strategies presented in this protocol will help to identify pertinent questions about one of the main therapies used in hospital settings when it comes to SARS by COVID-19, which is the use of NIV as a way to avoid OTI to promote health based on scientific evidence and develop further knowledge on the subject.

It is also intended to inform the scientific, academic, and professional community of the current state of existing literature and identify possible gaps regarding the content studied, and thereby reference and/or study circumstantial suggestions to complement these existing gaps in the treatment of SARS by COVID-19. In addition, this study will inform the proper development and use of this positive pressure therapy to promote an appropriate and effective intervention in hospitalized patients.

Acknowledgements

We thank the Laboratory of Studies and Research in Biological Signals (BIOSIGNAL) and the Fundação de Amparo à Pesquisa do Estado do Piauí (FAPEPI), which financed the project entitled "Functional and respiratory impacts on post-COVID-19 patients".

References

Brugge, S., Talman, S., Boonman-de Winter, L., de Mol, M., Hoefman, E., van Etten, R. W., & De Backer, I. C. (2021). Pulmonary function and health-related quality of life after COVID-19 pneumonia. Respiratory Medicine, 176, 106272. https://doi.org/10.1016/j.rmed.2020.106272 [ Links ]

Duan, J., Han, X., Bai, L., Zhou, L., & Huang, S. (2017). Assessment of heart rate, acidosis, consciousness, oxygenation, and respiratory rate to predict noninvasive ventilation failure in hypoxemic patients. Intensive Care Medicine, 43(2), 192-199. https://doi.org/10.1007/s00134-016-4601-3 [ Links ]

Gavriatopoulou, M., Ntanasis-Stathopoulos, I., Korompoki, E., Fotiou, D., Migkou, M., Tzanninis, I.-G., Psaltopoulou, T., Kastritis, E., Terpos, E., & Dimopoulos, M. A. (2021). Emerging treatment strategies for COVID-19 infection. Clinical and Experimental Medicine, 21(2), 167-179. https://doi.org/10.1007/s10238-020-00671-y [ Links ]

González-Castro, A., Fajardo Campoverde, A., Medina, A., & Alapont, V. (2021). Ventilación mecánica no invasiva y oxigenoterapia de alto flujo en la pandemia COVID-19: El valor de un empate. [Non-invasive mechanical ventilation and high-flow oxygen therapy in the COVID-19 pandemic: the value of a draw]. Medicina intensiva, 45(5), 320-321. https://doi.org/10.1016/j.medin.2020.04.01 [ Links ]

Grieco, D. L., Menga, L. S., Cesarano, M., Rosà, T., Spadaro, S., Bitondo, M. M., Montomoli, J., Falò, G., Tonetti, T., Cutuli, S. L., Pintaudi, G., Tanzarella, E. S., Piervincenzi, E., Bongiovanni, F., Dell’Anna, A. M., Delle Cese, L., Berardi, C., Carelli, S., Bocci, M. G. COVID-ICU Gemelli Study Group ,. (2021). Effect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure: The HENIVOT Randomized Clinical Trial. JAMA, 325(17), 1731-1743. https://doi.org/10.1001/jama.2021.4682 [ Links ]

Guia, M. F., Boléo-Tomé, J. P., Imitazione, P., Polistina, G. E., Alves, C., Ishikawa, O., Ballenberger, M., Mina, B., Fiorentino, G., Esquinas, A., & Scala, R. (2021). Usefulness of the HACOR score in predicting success of CPAP in COVID-19-related hypoxemia. Respiratory Medicine , 187, 106550. https://doi.org/10.1016/j.rmed.2021.106550 [ Links ]

Hraiech, S., Alingrin, J., Dizier, S., Brunet, J., Forel, J.-M., La Scola, B., Roch, A., Papazian, L., & Pauly, V. (2013). Time to Intubation Is Associated with Outcome in Patients with Community-Acquired Pneumonia. PLoS ONE, 8(9), e74937. https://doi.org/10.1371/journal.pone.0074937 [ Links ]

Mohamed, A. A., & Alawna, M. (2020). Role of increasing the aerobic capacity on improving the function of immune and respiratory systems in patients with coronavirus (COVID-19): A review. Diabetes & Metabolic Syndrome, 14(4), 489-496. https://doi.org/10.1016/j.dsx.2020.04.038 [ Links ]

Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G. & PRISMA Group ,. (2009). Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. PLoS Medicine, 6(7), e1000097. https://doi.org/10.1371/journal.pmed.1000097 [ Links ]

Murthy, S., Gomersall, C. D., & Fowler, R. A. (2020). Care for Critically Ill Patients With COVID-19. JAMA , 323(15), 1499-1500. https://doi.org/10.1001/jama.2020.3633 [ Links ]

Nava, S., Schreiber, A., & Domenighetti, G. (2011). Noninvasive ventilation for patients with acute lung injury or acute respiratory distress syndrome. Respiratory Care, 56(10), 1583-1588. https://doi.org/10.4187/respcare.01209 [ Links ]

Navarra, S. M., Congedo, M. T., & Pennisi, M. A. (2020). Indications for Non-Invasive Ventilation in Respiratory Failure. Reviews on Recent Clinical Trials, 15(4), 251-257. https://doi.org/10.2174/1574887115666200603151838 [ Links ]

Osadnik, C. R., Tee, V. S., Carson‐Chahhoud, K. V., Picot, J., Wedzicha, J. A., & Smith, B. J. (2017). Non‐invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease. The Cochrane Database of Systematic Reviews, 2017(7), CD004104. https://doi.org/10.1002/14651858.CD004104.pub4 [ Links ]

Peters, M.D.J., Godfrey, C., McInerney, P., Munn, Z., Tricco, A.C., & Khalil, H. (2020). Chapter 11: Scoping Reviews (2020 version). In: Aromataris E., & Munn Z. (Edits.). JBI Manual for Evidence Synthesis. Joanna Briggs Institute Reviewer's Manual. Available from https://synthesismanual.jbi.global. https://doi.org/10.46658/JBIMES-20-12 [ Links ]

Polak, S. B., Van Gool, I. C., Cohen, D., von der Thüsen, J. H., & van Paassen, J. (2020). A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression. Modern Pathology, 33(11), 2128-2138. https://doi.org/10.1038/s41379-020-0603-3 [ Links ]

Sharma, A., Ahmad Farouk, I., & Lal, S. K. (2021). COVID-19: A Review on the Novel Coronavirus Disease Evolution, Transmission, Detection, Control and Prevention. Viruses, 13(2), 202. https://doi.org/10.3390/v13020202 [ Links ]

Schünemann, H. J., Guyatt, G., Oxman, A. D., Akl, E. A., Kunz, R., Vist, G., Brozek, J., Norris, S., Falck-Ytter, Y., Glasziou, P., deBeer, H., Jaeschke, R., Rind, D., Meerpohl, J., & Dahm, P. (2013). Handbook for grading the quality of evidence and the strength of recommendations using the GRADE approach (Vol. 64). The GRADE Working Group. https://gdt.gradepro.org/app/handbook/handbook.html. [ Links ]

Spadari, J. A. A., & Gardenghi, G. (2020). Aspectos fisiopatológicos do COVID-19 e uso de ventilação não invasiva. É possível? Revista Pesquisa em Fisioterapia, 10(3), 372-375. https://doi.org/10.17267/2238-2704rpf.v10i3.3036 [ Links ]

Sullivan, Z. P., Zazzeron, L., Berra, L., Hess, D. R., Bittner, E. A., & Chang, M. G. (2022). Noninvasive respiratory support for COVID-19 patients: When, for whom, and how? Journal of Intensive Care, 10(1), 3. https://doi.org/10.1186/s40560-021-00593-1 [ Links ]

Wang, Z., Wang, Y., Yang, Z., Wu, H., Liang, J., Liang, H., Lin, H., Chen, R., Ou, Y., Wang, F., Wang, Y., Wang, Y., Luo, W., Li, N., Li, Z., Xie, J., Jiang, M., & Li, S. (2021). The use of non-invasive ventilation in COVID-19: A systematic review. International Journal of Infectious Diseases: IJID: Official Publication of the International Society for Infectious Diseases, 106, 254-261. https://doi.org/10.1016/j.ijid.2021.03.078 [ Links ]

Wendel-Garcia, P. D., Mas, A., González-Isern, C., Ferrer, R., Máñez, R., Masclans, J.-R., Sandoval, E., Vera, P., Trenado, J., Fernández, R., Sirvent, J.-M., Martínez, M., Ibarz, M., Garro, P., Lopera, J. L., Bodí, M., Yébenes-Reyes, J. C., Triginer, C., Vallverdú, I., UCIsCAT study group. (2022). Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: A multicenter observational retrospective study. Critical Care, 26(1), 37. https://doi.org/10.1186/s13054-022-03905-5 [ Links ]

Weng, C.-L., Zhao, Y.-T., Liu, Q.-H., Fu, C.-J., Sun, F., Ma, Y.-L., Chen, Y.-W., & He, Q.-Y. (2010). Meta-analysis: Noninvasive Ventilation in Acute Cardiogenic Pulmonary Edema. Annals of Internal Medicine, 152(9), 590-600. https://doi.org/10.7326/0003-4819-152-9-201005040-00009 [ Links ]

Windisch, W., Weber-Carstens, S., Kluge, S., Rossaint, R., Welte, T., & Karagiannidis, C. (2020). Invasive and Non-Invasive Ventilation in Patients With COVID-19. Deutsches Ärzteblatt International, 117(31-32), 528-533. https://doi.org/10.3238/arztebl.2020.0528 [ Links ]

Yilma, M., Taye, G., Kifle, A., Ayele, W., & Biruk, E. (2021). Hospitalization, Recovery, Death, incubation period and Severity of COVID-19: A Systematic Review. Ethiopian Journal of Health Development, 35(1), Article 1. https://www.ajol.info/index.php/ejhd/article/view/210759Links ]

Zhan, Q., Sun, B., Liang, L., Yan, X., Zhang, L., Yang, J., Wang, L., Ma, Z., Shi, L., Wei, L., Li, G., Yang, L., Shi, Z., Chen, Y., Xu, Q., Li, W., Zhu, X., Wang, Z., Sun, Y., Wang, C. (2012). Early use of noninvasive positive pressure ventilation for acute lung injury: A multicenter randomized controlled trial. Critical Care Medicine, 40(2), 455-460. https://doi.org/10.1097/CCM.0b013e318232d75e [ Links ]

Received: September 06, 2022; Accepted: September 19, 2022

Corresponding Author Sara Sabrina Vieira Cirilo Avenida Deputado Pinheiro Machado, 822, apto 102, Bairro Pindorama 64215-293 - Parnaíba-PI - Brasil vieira.sarasabrina@ufpi.edu.br

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